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The weight loss drug Qnexa is likely to be approve by the Food and Drug Administration in the next month , expert say .
Last workweek , an FDA panel vote in favour of the drug ’s approval , and the agency usually follows the advice of its panels . The decisiveness is a turn - around from a string of recent disapprovals for similar drugs , including theweight - loss drug Contrave , which was rejected by the FDA last year .
But is Qnexa a pragmatic manner to lose weighting ? Here ’s what five free weight - loss experts had to say .
Dr. Pieter Cohen , assistant prof of medicine at Harvard Medical School and a world-wide internist at Cambridge Health Alliance :
" It ’s likely that the FDA will soon approve Qnexa forweight deprivation . This is unfortunate . Qnexa does help oneself some hoi polloi fall behind a modest amount of weight , but to keep the weight off , one has to take Qnexa for a lifetime . But we have no idea if Qnexa is safe to practice for a lifetime . In fact , there are many early finding that suggest it might direct to serious health job such as seizures , parentage defects , kidney stones , disarray and heart disease .
" In my judgment , it is likely that Qnexa will follow in the footsteps of Meridia . Meridia was boast as a magic heater for safe weight deprivation only to bewithdrawn from the U.S.after heedful work revealed that it actually increased the risk of heart attacks and strokes .
" Assuming Qnexa is approved , what do I recommend ? It will be very tempting to try a new dieting anovulant once the FDA gives it their blessing , but in the case of Qnexa : just say no . Stick with the voiceless employment of increasing utilisation , modestly decrease calories and choose healthy foods .
" For sure people , stomachal bypass might be the right answer , but there ’s not a pill around that ’s deserving its exercising weight . "
Dr. Olveen Carrasquillo , chief of general medicament at the University of Miami Miller School of Medicine :
" Qnexa , like other such factor , can definitely attain unforesightful - term weight loss . The big doubt is whether that short - condition free weight loss is lasting … over several class . In fact , periodically going up and down in system of weights is probably more dangerous than defend a stable weight .
Further , what I would need to know is if the weightiness [ stays ] off over several years . Then , does it also lead in improved health resultant over the long term — less diabetes , less high blood pressure , ameliorate wellness and functional status and lower mortality charge per unit over several years .
" If the drug does not top to tenacious - condition lifestyle change , I am doubtful of any such long - term welfare .
" Like many other doctors , I do my secure to obviate prescribing any raw mediations for the first few year after approval , unless they are vital . This allows meter to have full brand merchandising data on foresightful - term side effects .
" Also , I would be extremely leery of using this drug in any woman of child - bearing geezerhood . "
Dr. David Katz , theater director of the Prevention Research Center at Yale University School of Medicine :
Yes , [ Quenexa ] can serve you lose weight . But that does n’t mean it will , or even that it should .
Qnexa combines a stimulant drug with an anti - epilepsy drug . The first can aim up rip pressure sensation , and can [ cause ] restiveness . The second can make fatigue , nausea and brain fog . It ’s not a great drug by any means , and probably only works as long as people keep taking it .
For those facingbariatric surgical operation , it is an option worth take , although not as effective . For most others , better utilisation of feet and crotch is the far better option .
Dr. Michael Aziz , internist at Lenox Hill Hospital in New York City :
" Qnexa combines phentermine ( the other one-half of fenland - phen ) and topiramate ( sell as Topamax ) . When Qnexa was compared with a placebo pill , weightiness loss patients that were care for with Qnexa for two yr show up step-down in lineage insistency , in addition to prescribed improvement in lipid storey following reductions in weighting loss . However , there are other concerns , such as psychiatric problems , as well as issues with parentage defects .
" Phentermine is jazz to cause elevation in blood pressure . Topamax has [ more ] serious side effects which are described in drug safety inserts and they let in : paresthesia or " pins and needles , " most often in the arm or legs , fatigue , gustation modification , difficultness with concentration and weight unit loss . Now we can understand how weight loss became a suitable side impression to combine this Topamax with phentermine .
" Yes , Qnexa may help many , but lifestyle and the correct diet should be the first focus and primary targets to address for those who are scramble with weight and ask a genuine , and a lasting solution . "
Dr. Sunil Bhoyrul , bariatric surgeon at Scripps Memorial Hospital in La Jolla , Calif.
" Any scheme to help oneself citizenry lose weight should be seriously considered . [ But ] it ’s oversimplify to say give everyone Qnexa .
" For the Clarence Shepard Day Jr. to day reality of strike fear of affected role , we know that you need a whole array of intervention option . "
